Effect of age and extent of dietary restriction on hepatic microsomal lipid peroxidation potential in mice.

@article{Davis1993EffectOA,
  title={Effect of age and extent of dietary restriction on hepatic microsomal lipid peroxidation potential in mice.},
  author={Lizabeth Jane Davis and Bruna Tadolini and Pier Luigi Biagi and Roy L. Walford and Federico Licastro},
  journal={Mechanisms of ageing and development},
  year={1993},
  volume={72 2},
  pages={155-63}
}
Lipid peroxidation potential in hepatic microsomes from young and old mice following two different caloric restriction regimens was measured by a colorimetric thiobarbituric acid method under conditions where Fe2+ autoxidation and free oxygen radical production were undetectable. Peroxidation was highest in the young (3.5-month-old) slightly restricted group (caloric intake 75% of ad libitum mice) but very low in young severely restricted (caloric intake 50% of ad libitum mice) and in both old… CONTINUE READING

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