Effect of age and blood pressure on the heart rate, vasopressin, and renin response to hypoxia in fetal sheep.
@article{Raff1992EffectOA, title={Effect of age and blood pressure on the heart rate, vasopressin, and renin response to hypoxia in fetal sheep.}, author={H. Raff and C. Wood}, journal={The American journal of physiology}, year={1992}, volume={263 4 Pt 2}, pages={ R880-4 } }
The purpose of these studies was to determine whether attenuating the increase in arterial and central venous pressure (CVP) during acute hypoxia can augment the renin and arginine vasopressin (AVP) responses to isocapnic hypoxia in chronically instrumented sheep fetuses. Young (122 +/- 2 days; n = 7) and old (133 +/- 1 days, n = 7) fetuses were exposed to hypoxemia (arterial PO2 = approximately 12-13 Torr) without and with attenuation of the increase in mean arterial pressure (MAP) and CVP… CONTINUE READING
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