Effect of administration of corticotropin-releasing hormone and glucocorticoid on arginine vasopressin response to osmotic stimulus in normal subjects and patients with hypocorticotropinism without overt diabetes insipidus.

@article{Yamada1989EffectOA,
  title={Effect of administration of corticotropin-releasing hormone and glucocorticoid on arginine vasopressin response to osmotic stimulus in normal subjects and patients with hypocorticotropinism without overt diabetes insipidus.},
  author={K. Yamada and Yasushi Tamura and S Yoshida},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1989},
  volume={69 2},
  pages={
          396-401
        }
}
We examined the effect of CRH administration on the response of plasma arginine vasopressin (AVP) induced by an osmotic stimulus in six normal subjects and five patients with hypocorticotropinism without overt diabetes insipidus (four patients with Sheehan's syndrome and one with idiopathic pituitary dwarfism with ACTH deficiency). Hypertonic saline infusion (855 mmol/L saline solutions at a rate of 205 mumol/kg.min for 10 min) increased plasma AVP 5.7-fold (P less than 0.01) in normal subjects… 
21 Citations
Testosterone normalizes plasma vasopressin response to osmotic stimuli in men with hypogonadism.
TLDR
It is suggested that testosterone improves the subnormal vasopressin response to osmotic stimuli in men with hypogonadism, and plasma vasopressingin concentrations during hypertonic saline infusions are determined.
Testosterone Normalizes Plasma Vasopressin Osmotic Stimuli in Men with Hypogonadism Response to
TLDR
It is suggested that testosterone improves the subnormal vasopressin response to osmotic stimuli in men with hypogonadism and reduces the risk of developing diabetes insipidus.
Corticotrophin releasing hormone (CRH1–41) stimulates the secretion of adrenocorticotrophin, vasopressin and oxytocin but not adrenocorticotrophin precursors: evidence from petrosal sinus sampling in man
TLDR
The relation between plasma AVP and corticosteroids seen in clinical hypoadrenal states could be explained by chronic stimulation of AVP secretion by CRH, and observations suggest a novel relationship between AVP, OXT and CRH in the regulation of ACTH secretion in man.
Dehydration, but not vasopressin infusion, enhances the adrenocortical responses of sheep to corticotropin-releasing hormone or restraint.
TLDR
Pituitary responsiveness to exogenous or endogenous CRH (restraint stress) may be enhanced in sheep by dehydration through a mechanism that does not involve an adrenal or pituitary action of circulating AVP.
Psychotic exacerbations and enhanced vasopressin secretion in schizophrenic patients with hyponatremia and polydipsia.
TLDR
Psychotic exacerbations are associated with enhanced antidiuretic hormone secretion, for unknown reasons, in schizophrenic patients with hyponatremia and polydipsia, thereby placing them at increased risk of life-threatening water intoxication.
Dual facets of hyponatraemia and arginine vasopressin in patients with ACTH deficiency
TLDR
This work attempted to assess volume status from changes in selected clinical measurements related to body fluid balance in the course of i.v. fluid supplementation and following glucocorticoid replacement in ACTH‐deficient patients, and to interpret plasma AVP levels in the context of the estimated volume status.
Interactions between Neurohypophysial Hormones and the ACTH‐Adrenocortical Axis a
  • H. Raff
  • Biology, Medicine
    Annals of the New York Academy of Sciences
  • 1993
TLDR
It is now clear that hormones from the posterior pituitary can influence the secretion of ACTH via the short portal circulation and, possibly, by recirculation.
A case report of hypodipsic hypernatremia syndrome associated with suprasellar tumor.
TLDR
Dissociation in the plasma vasopressin response to osmotic change and hemodynamic change was demonstrated in this patient, presumably associated with pathologic conditions in or around the hypothalamus.
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TLDR
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TLDR
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TLDR
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