Effect of adherence to HAART on virologic outcome and on the selection of resistance-conferring mutations in NNRTI- or PI-treated patients.

@article{Maggiolo2007EffectOA,
  title={Effect of adherence to HAART on virologic outcome and on the selection of resistance-conferring mutations in NNRTI- or PI-treated patients.},
  author={Franco Maggiolo and Monica Airoldi and Hendrik Dani{\"e}l Kleinloog and Annapaola Callegaro and Veronica Ravasio and Claudio Arici and Enrico Bombana and Fredy Suter},
  journal={HIV clinical trials},
  year={2007},
  volume={8 5},
  pages={282-92}
}
BACKGROUND The effect of adherence on the risk of virologic failure and mutations selection was verified in a prospective study. METHOD At baseline, all patients had a viral load (VL) <50 copies/mL and completed a self-reported questionnaire. Patients were followed for the subsequent 4 months to document virologic rebound (VL > 50 copies/mL). RESULTS 1,133 patients completed 2,240 questionnaires/follow-up (non-nucleoside reverse transcriptase inhibitor [NNRTI] = 1,479; single protease… CONTINUE READING