Effect of adenosine on pulmonary circulation of rabbits.

  title={Effect of adenosine on pulmonary circulation of rabbits.},
  author={Hassan A. El-kashef and Mohamed M. A. Elmazar and Othman Abdualla Al-Shabanah and Abdullah M. Al-Bekairi},
  journal={General pharmacology},
  volume={32 3},
The effect and mechanism of action of adenosine on the pulmonary circulation of rabbits were studied. Adenosine (10(-5)-10(-3) M) produced a concentration-dependent decrease in pulmonary arterial tension of precontracted pulmonary arterial rings. Removal of endothelium (denuded) augmented the adenosine-induced vasodilation in the pulmonary arterial rings… CONTINUE READING