Effect of adenosine and adenosine agonists on amylase release from rat pancreatic lobules.

@article{RodrguezNodal1995EffectOA,
  title={Effect of adenosine and adenosine agonists on amylase release from rat pancreatic lobules.},
  author={F Rodr{\'i}guez-Nodal and Jos{\'e} Ignacio San Rom{\'a}n and Jos{\'e} Miguel L{\'o}pez-Novoa and Jos{\'e} Juli{\'a}n Calvo},
  journal={Life sciences},
  year={1995},
  volume={57 17},
  pages={PL253-8}
}
The effects of adenosine on the amylase secretion from rat pancreatic lobules have been studied. Adenosine induces a dose-dependent stimulation on amylase release, which is maximal at a concentration of 10(-4) M. It has been observed a clear inhibition of this secretory action when atropine was added whereas no amylase release was seen in isolated acini after adenosine. The effect of adenosine is completely blocked by the adenosine receptors antagonist theophylline (10(-4) M), but not by… CONTINUE READING

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