Effect of acute desmopressin and of long-term thyroxine replacement on haemostasis in hypothyroidism.

OBJECTIVE Hypothyroidism can be complicated by bleeding symptoms such as easy bruising, menorrhagia and sometimes even a severe bleeding tendency with fatal outcome. Usually there is a prolonged bleeding time, or a low plasma concentration of coagulation factor VIII (FVIII) or von Willebrand factor (vWF). The aim of the present study was to investigate the… CONTINUE READING