Effect of acute Yersinia enterocolitica infection on small intestinal ultrastructure.

@article{Buret1990EffectOA,
  title={Effect of acute Yersinia enterocolitica infection on small intestinal ultrastructure.},
  author={Alain Buret and Edward O'loughlin and Garniss H. Curtis and Dietrich Gall},
  journal={Gastroenterology},
  year={1990},
  volume={98 6},
  pages={1401-7}
}
The purpose of this study was to assess the jejunal and ileal brush border injury caused by Yersinia enterocolitica and to correlate these alterations with functional abnormalities. Weanling rabbits infected with 10(10) organisms of a human pathogenic Y. enterocolitica strain were compared with control and pair-fed, sham-treated animals. On day 6, infection resulted in a diffuse decrease in brush border enzyme activities in the small intestine and villus atrophy and crypt hyperplasia in the… CONTINUE READING