Effect of activated charcoal administration on acetylcysteine serum levels in humans.

@article{North1981EffectOA,
  title={Effect of activated charcoal administration on acetylcysteine serum levels in humans.},
  author={Donald S. North and Robert G. Peterson and Edward P. Krenzelok},
  journal={American journal of hospital pharmacy},
  year={1981},
  volume={38 7},
  pages={
          1022-4
        }
}
  • Donald S. North, Robert G. Peterson, Edward P. Krenzelok
  • Published 1981
  • Medicine
  • American journal of hospital pharmacy
  • The effect of orally administered activated charcoal on the absorption of acetylcysteine in three men was studied. Each of the three volunteers was given 140 mg/kg acetylcysteine as a single oral dose. Blood samples were taken at 0, 0.5, 1, 1.5, 2, 4, 6, and 8 hours after acetylcysteine ingestion. Following a one-week washout period, each subject was given orally 50 g of Activated Charcoal, USP, 15 minutes before a 140-mg/kg acetylcysteine oral dose. Blood samples were taken. Acetylcysteine… CONTINUE READING