Effect of action potential duration and conduction velocity restitution and their spatial dispersion on alternans and the stability of arrhythmias.

@article{Banville2002EffectOA,
  title={Effect of action potential duration and conduction velocity restitution and their spatial dispersion on alternans and the stability of arrhythmias.},
  author={Isabelle Banville and Richard A. Gray},
  journal={Journal of cardiovascular electrophysiology},
  year={2002},
  volume={13 11},
  pages={1141-9}
}
INTRODUCTION The slope of the action potential duration (APD) restitution curve has been used to explain wavebreaks during arrhythmia initiation and maintenance. This hypothesis remains incomplete to fully describe the experimental data. Other factors contributing to wavebreaks must be studied to further understand arrhythmia dynamics. METHODS AND RESULTS Control APDs were measured from isolated rabbit hearts using a monophasic action potential probe. APD and conduction velocity (CV… CONTINUE READING

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