Effect of acetylsalicylic acid on the constituents of the gastric mucosal barrier.

Abstract

The effect of luminal application of acetylsalicylic acid (ASA) on the liberation of gastric mucosal barrier constituents at pH 5.0 and 2.0 was investigated. The Lucite chamber stomach-flap preparation was used in 18 dogs whose basal H+ secretion was inhibited by cimetidine. An ASA dose of 10 mmol at pH 5.0 caused a moderate increase in content of proteins… (More)

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Cite this paper

@article{Sarosiek1984EffectOA, title={Effect of acetylsalicylic acid on the constituents of the gastric mucosal barrier.}, author={Justyna Sarosiek and Bronislaw L. Slomiany and J. Świerczek and Amalia Slomiany and Zbigniew W J{\'o}źwiak and Stanisław Jan Konturek}, journal={Scandinavian journal of gastroenterology}, year={1984}, volume={19 2}, pages={150-3} }