Effect of acetylsalicylic acid on platelet activation and oxidative profile in a set of Brazilian patients with type 2 diabetes mellitus.

@article{Duarte2015EffectOA,
  title={Effect of acetylsalicylic acid on platelet activation and oxidative profile in a set of Brazilian patients with type 2 diabetes mellitus.},
  author={Rita Carolina Figueiredo Duarte and Lillian Harboe Gonçalves and Fernanda M F Campos and Olindo Assis Martins Filho and Michelle Teodoro Alves and Ana Paula Fernandes and Karina Braga Gomes Borges and Luci M S Dusse and Mayara C. Faria and Gisele Santos Gonçalves and Adriana Ap Bosco and Valeria Cristina Sandrim and Maria das Graças Carvalho},
  journal={Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis},
  year={2015},
  volume={26 2},
  pages={
          123-30
        }
}
Type 2 diabetes mellitus (DM2) is a metabolic disorder associated with hyperactivation of platelets, increased formation of platelet microparticles (PMPs) and oxidative stress that are related to cardiovascular complications. Acetylsalicylic acid (ASA) is an antiplatelet agent used in the prevention of atherothrombosis. The aim of this study was to evaluate the effect of ASA by means of platelet activation and oxidative profile. We collected blood samples of 81 patients with DM2 before and… CONTINUE READING

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