Effect of acetylsalicylic acid on platelet activation and oxidative profile in a set of Brazilian patients with type 2 diabetes mellitus

@article{Duarte2015EffectOA,
  title={Effect of acetylsalicylic acid on platelet activation and oxidative profile in a set of Brazilian patients with type 2 diabetes mellitus},
  author={R. Duarte and L. Gonçalves and Fernanda M F Campos and O. A. M. Filho and M. Alves and A. P. Fernandes and K. B. G. Borges and L. Dusse and Mayara C. Faria and G. S. Gonçalves and A. Bosco and V. Sandrim and M. Carvalho},
  journal={Blood Coagulation & Fibrinolysis},
  year={2015},
  volume={26},
  pages={123–130}
}
  • R. Duarte, L. Gonçalves, +10 authors M. Carvalho
  • Published 2015
  • Medicine
  • Blood Coagulation & Fibrinolysis
  • Type 2 diabetes mellitus (DM2) is a metabolic disorder associated with hyperactivation of platelets, increased formation of platelet microparticles (PMPs) and oxidative stress that are related to cardiovascular complications. Acetylsalicylic acid (ASA) is an antiplatelet agent used in the prevention of atherothrombosis. The aim of this study was to evaluate the effect of ASA by means of platelet activation and oxidative profile. We collected blood samples of 81 patients with DM2 before and… CONTINUE READING
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