Effect of acarbose, an alpha-glucosidase inhibitor, on serum lipoprotein lipase mass levels and common carotid artery intima-media thickness in type 2 diabetes mellitus treated by sulfonylurea.

@article{Oyama2008EffectOA,
  title={Effect of acarbose, an alpha-glucosidase inhibitor, on serum lipoprotein lipase mass levels and common carotid artery intima-media thickness in type 2 diabetes mellitus treated by sulfonylurea.},
  author={Tomokazu Oyama and Atsuhito Saiki and Kei Endoh and Noriko Ban and Daizi Nagayama and Masahiro Ohhira and Nobukiyo Koide and Yoh Miyashita and Kohji Shirai},
  journal={Journal of atherosclerosis and thrombosis},
  year={2008},
  volume={15 3},
  pages={154-9}
}
AIM Previous reports indicate that serum lipoprotein lipase mass levels (LPL mass) and common carotid artery intima-media thickness (CCA-IMT) are independent predictors of atherosclerotic diseases. The aim of this study was to examine the effects of combination therapy of sulfonylurea and acarbose on LPL mass and CCA-IMT. METHODS Eighty-four patients with type 2 diabetes mellitus, who were treated with only sulfonylureas and showed CCA-IMT of more than 0.9 mm at baseline, were selected and… CONTINUE READING

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