Effect of abnormal mineralization on the mechanical behavior of X-linked hypophosphatemic mice femora.

@article{Camacho1995EffectOA,
  title={Effect of abnormal mineralization on the mechanical behavior of X-linked hypophosphatemic mice femora.},
  author={Nancy Pleshko Camacho and Clare M. Rimnac and Ronald A. Meyer and Stephen R. Doty and Adele L. Boskey},
  journal={Bone},
  year={1995},
  volume={17 3},
  pages={
          271-8
        }
}
The Hyp mouse is an established animal model of X-linked hypophosphatemia, one of the most common genetic forms of metabolic bone disease in humans. This study describes the first determination of whole bone mechanical behavior in the heterozygous male and female Hyp mouse. Femora from 12-week-old mice were tested in torsion. The contribution of structural and material properties to mechanical behavior was determined by geometrical evaluation prior to testing and by analysis of the diaphyseal… CONTINUE READING

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