Effect of a topical diclofenac solution for relieving symptoms of primary osteoarthritis of the knee: a randomized controlled trial.

@article{Bookman2004EffectOA,
  title={Effect of a topical diclofenac solution for relieving symptoms of primary osteoarthritis of the knee: a randomized controlled trial.},
  author={Arthur A M Bookman and Kate Williams and J. Zev Shainhouse},
  journal={CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne},
  year={2004},
  volume={171 4},
  pages={333-8}
}
BACKGROUND Treatment of osteoarthritis with oral NSAID therapy provides pain relief but carries a substantial risk of adverse effects. Topical NSAID therapy offers an alternative to oral treatment, with the potential for a reduced risk of side effects. The objective of this trial was to assess the safety and efficacy of a topical diclofenac solution in relieving the symptoms of primary osteoarthritis of the knee. METHODS We identified 248 men and women from southern Ontario with primary… CONTINUE READING

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