Effect of a statin on an in vitro model of endometriosis.

  title={Effect of a statin on an in vitro model of endometriosis.},
  author={Navid Esfandiari and Mozafar Khazaei and Jafar Ai and Ryszard Bielecki and Lynda Gotlieb and Edward A J Ryan and Robert F. Casper},
  journal={Fertility and sterility},
  volume={87 2},
OBJECTIVE To determine the inhibitory effect of a statin on angiogenesis in a three-dimensional (3-D) culture of human endometrial fragments in vitro. Angiogenesis has been proposed as an important mechanism in the pathogenesis of endometriosis, and statins (3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors) have been shown to have anti… CONTINUE READING