Effect of a phospho-oligosaccharidic putative insulin messenger on insulin release in rats

Abstract

The phospho-oligosaccharide extracted from rat liver and supposed to act as the insulin second messenger inhibits glucose-stimulated insulin release. In the present study, this phospho-oligosaccharide was found not to affect D-[U-14C]glucose oxidation and 45Ca net uptake, but to inhibit insulin release evoked by either D-glucose or 2-ketoisocaproate in… (More)
DOI: 10.1007/BF00265545

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