Effect of a novel nuclear factor-κB activation inhibitor on renal ischemia-reperfusion injury.

@article{Kono2013EffectOA,
  title={Effect of a novel nuclear factor-κB activation inhibitor on renal ischemia-reperfusion injury.},
  author={Hidaka Kono and Ken Nakagawa and Shinya Morita and Kazunobu Shinoda and Ryuichi Mizuno and Eiji Kikuchi and Akira Miyajima and Kazuo Umezawa and Mototsugu Oya},
  journal={Transplantation},
  year={2013},
  volume={96 10},
  pages={863-70}
}
BACKGROUND In kidney transplantation, the relationship between prolonged warm or cold ischemic storage of kidneys and a higher incidence of delayed graft function is previously known, and delayed graft function has been known to aggravate poor long-term graft survival. We investigated the effect of a novel nuclear factor-κB activation inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ), on renal ischemia-reperfusion (I/R) injury. METHODS DHMEQ was administered to Lewis rats once just before… CONTINUE READING
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