Effect of a nonsedative dose of propofol on memory for aversively loaded information in rats.

  title={Effect of a nonsedative dose of propofol on memory for aversively loaded information in rats.},
  author={Laure Pain and Marie-Jos{\'e}e Angst and Laurence LeGourrier and Philippe Oberling},
  volume={97 2},
BACKGROUND The effects of propofol on memory for aversive information are not well determined. The authors evaluated the effects of a minimal nonsedative dose of propofol or midazolam on memory in rats, using an apparatus composed of two compartments: a large bright anxiogenic one and a small dark neutral one. METHODS Groups of rat received propofol (9 mg/kg, intraperitoneally) or midazolam (3 mg/kg). Anxiety was assessed in rats placed in the anxiogenic compartment as the time before the… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 13 extracted citations


Publications referenced by this paper.
Showing 1-10 of 39 references

Effect of midazolam on memory for an aversive event: Sedative, affective or mnemonic processes? Memory and Awareness in Anaesthesia IV. Edited by Jordan C, Vaughan DJA, Newton DEF

  • L Pain, A Launoy, P Oberling
  • 2000
Highly Influential
5 Excerpts

phobias, and preparedness: Toward an evolved module of fear and fear learning

  • A Ohman, Mineka S Fears
  • Psychol Rev
  • 2001

A comparison of the effects of propofol and midazolam on memory during two levels of sedation by using target-controlled infusion

  • A De Roode, JMA van Gerven, +5 authors JG Bovill
  • Anesth Analg
  • 2000

Conscious sedation in patients undergoing surgical and investigational procedures

  • TT Randell, JV Kyttä
  • CNS Drugs
  • 2000

Similar Papers

Loading similar papers…