Effect of a mistletoe extract (Iscador® QuFrF) on viability and migratory behavior of human peripheral CD4+ and CD8+ T lymphocytes in three-dimensional collagen lattices

@article{Nikolai1997EffectOA,
  title={Effect of a mistletoe extract (Iscador® QuFrF) on viability and migratory behavior of human peripheral CD4+ and CD8+ T lymphocytes in three-dimensional collagen lattices},
  author={G. Nikolai and Peter Friedl and M. Werner and Bernd Niggemann and Kurt S. Zaenker},
  journal={In Vitro Cellular & Developmental Biology - Animal},
  year={1997},
  volume={33},
  pages={710-716}
}
Migration and tissue distribution of immunocompetent cells may be critical prerequisites for efficient immune surveillance. The effect of various concentrations of the mistletoe extract Iscador® QuFrF on the locomotory behavior and viability of immunomagnetically isolated human CD4+ and CD8+ T lymphocytes within three-dimensional collagen gels was investigated. Although variation in baseline activities of spontaneously migrating T cells was donor-dependent, a dose-dependent stimulation of the… CONTINUE READING
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