Effect of a gonadotropin releasing hormone analog on an experimental ovarian tumor: direct and indirect actions.

@article{LuxLantos1995EffectOA,
  title={Effect of a gonadotropin releasing hormone analog on an experimental ovarian tumor: direct and indirect actions.},
  author={Victoria A Lux-Lantos and Sandra M Thyssen and Annette Chamson and Carlos Libertun},
  journal={Life sciences},
  year={1995},
  volume={57 3},
  pages={291-300}
}
An ovary autotransplanted into the spleen of a bilaterally ovariectomized rat develops into a luteoma, which grows under constant gonadotropin hyperstimulation. The effect of a long-acting GnRH agonist (GnRH-a), on tumor growth and hormone secretion was investigated. Two experimental models were used: Model 1: GnRH-a (0.33 mg/rat sc) or estradiol valerianate (50 micrograms/rat sc injected once a week for four weeks) was administered simultaneously with ovary implantation; Model 2: the drugs… CONTINUE READING
4 Citations
0 References
Similar Papers