Effect of a 1-week treatment with 0.5% topical fluorouracil on occurrence of actinic keratosis after cryosurgery: a randomized, vehicle-controlled clinical trial.

@article{Jorizzo2004EffectOA,
  title={Effect of a 1-week treatment with 0.5% topical fluorouracil on occurrence of actinic keratosis after cryosurgery: a randomized, vehicle-controlled clinical trial.},
  author={Joseph Lucius Jorizzo and Jonathan Weiss and K. Furst and Christine J Vandepol and Sharon F. Levy},
  journal={Archives of dermatology},
  year={2004},
  volume={140 7},
  pages={813-6}
}
BACKGROUND No long-term randomized controlled clinical trial has compared the efficacy of cryosurgery alone vs cryosurgery following fluorouracil applications for the treatment of actinic keratosis. OBJECTIVE To determine the 6-month outcome of a 1-week course of 0.5% fluorouracil followed by cryosurgery. DESIGN Prospective, multicenter, randomized, double-blind, vehicle-controlled clinical trial performed in community and academic outpatient clinics. PATIENTS A total of 144 patients with… CONTINUE READING

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