• Corpus ID: 207994799

Effect of Zingiber officinale on spasm

  title={Effect of Zingiber officinale on spasm},
  author={Nadia Hisamuddin and Nur Nadhirah Kamarudin and Mohd. Roslan Sulaiman and Wan Mastura Shaik Mossadeq},
Zingiberaceae is one of the largest plant families consisting of rhizomes that are commonly used as spice in soups and curries as well as alternative medications in folklore medicine. Zingiber officinale or commonly known as ginger is extensively employed in Asian, Ayurvedic, Chinese, and Arabian folklore medicine for the treatment of pain, inflammation and various spasm-associated gastric ailments. The past few decades saw rapid advancements in the extraction process of ginger bioactive… 


Medicinal properties of Ginger (Zingiber officinale Rosc.)
After extensive pharmacological studies, it has been concluded that ginger has significant antiinflammatory, anti-emetic and chemo-protective effects.
Zingiberis rhizoma: a comprehensive review on the ginger effect and efficacy profiles.
Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research.
  • B. Ali, G. Blunden, M. Tanira, A. Nemmar
  • Medicine
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2008
Pharmacological Basis for the Medicinal Use of Ginger in Gastrointestinal Disorders
Data indicate that Zo.Cr contains a cholinergic, spasmogenic component evident in stomach fundus preparations which provides a sound mechanistic insight for the prokinetic action of ginger.
The study of the antispasmodic effect of Ginger (Zingiber officinale) in vitro
The results revealed that the effect of low doses of ginger on exogenous acetyl choline (ACh) induced contraction is spasmogenic as a dose of 0.2ml=20μg of ginger / tissue bath produced increase in the magnitude of ach induced contraction from 0.91 to 1.11.
Inhibitory effects of zingerone, a pungent component of Zingiber officinale Roscoe, on colonic motility in rats
It is suggested that zingerone might exert beneficial therapeutic effects on hypermotility-induced diarrhea by abrogating excessive gastrointestinal motility through direct action on smooth muscles.
Pharmacological evaluation of a polyherbal formulation for its antispasmodic activity
It is concluded that polyherbal formulation inhibits the contraction produced by various spasmogens like acetylcholine and calcium chloride, which suggests that the activity of developed formulation is nonspecific to any spasmogen.