Effect of WIN 55212-2, a cannabinoid receptor agonist, on aqueous humor dynamics in monkeys.

@article{Chien2003EffectOW,
  title={Effect of WIN 55212-2, a cannabinoid receptor agonist, on aqueous humor dynamics in monkeys.},
  author={Fred Y Chien and Rong-fang Wang and Thomas Wesley Mittag and Steven M. Podos},
  journal={Archives of ophthalmology},
  year={2003},
  volume={121 1},
  pages={87-90}
}
OBJECTIVE To evaluate the effects of WIN 55212-2, a cannabinoid receptor agonist, on intraocular pressure and aqueous humor dynamics in normal monkeys and monkeys with glaucoma. METHODS Intraocular pressure was measured prior to and up to 6 hours after the topical administration of WIN 55212-2 to 1 eye of 5 normal monkeys and to the glaucomatous eye of 8 monkeys with unilateral laser-induced glaucoma. Tonographic outflow facility and fluorophotometric flow rates of aqueous humor were measured… CONTINUE READING
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