Effect of Ursodeoxycholic Acid Use on the Risk of Colorectal Neoplasia in Patients with Primary Sclerosing Cholangitis and Inflammatory Bowel Disease: A Systematic Review and Meta-analysis

@article{Singh2013EffectOU,
  title={Effect of Ursodeoxycholic Acid Use on the Risk of Colorectal Neoplasia in Patients with Primary Sclerosing Cholangitis and Inflammatory Bowel Disease: A Systematic Review and Meta-analysis},
  author={S. Singh and S. Khanna and D. Pardi and E. Loftus and J. Talwalkar},
  journal={Inflammatory Bowel Diseases},
  year={2013},
  volume={19},
  pages={1631–1638}
}
  • S. Singh, S. Khanna, +2 authors J. Talwalkar
  • Published 2013
  • Medicine
  • Inflammatory Bowel Diseases
  • Background: Ursodeoxycholic acid (UDCA) may modify the risk of inflammatory bowel disease (IBD)–associated colorectal cancer. We performed a systematic review and meta-analysis of studies evaluating the effect of UDCA on the risk of IBD-associated colorectal neoplasia (CRN) (defined as colorectal cancer and/or dysplasia) in patients with primary sclerosing cholangitis with concomitant IBD (PSC-IBD). Methods: We conducted a systematic search of Medline, Embase, and Web of Science and manually… CONTINUE READING
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