Effect of Uric Acid-Lowering Agents on Endothelial Function: A Randomized, Double-Blind, Placebo-Controlled Trial.

@article{Borgi2017EffectOU,
  title={Effect of Uric Acid-Lowering Agents on Endothelial Function: A Randomized, Double-Blind, Placebo-Controlled Trial.},
  author={Lea Borgi and Ciaran J McMullan and Ann L. Wohlhueter and Gary C. Curhan and Naomi D L Fisher and John P. Forman},
  journal={Hypertension},
  year={2017},
  volume={69 2},
  pages={
          243-248
        }
}
Higher levels of serum uric acid are independently associated with endothelial dysfunction, a mechanism for incident hypertension. Overweight/obese individuals are more prone to endothelial dysfunction than their lean counterparts. However, the effect of lowering serum uric acid on endothelial dysfunction in these individuals has not been examined thoroughly. In this randomized, double-blind, placebo-controlled trial of nonhypertensive, overweight, or obese individuals with higher serum uric… CONTINUE READING

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