Effect of UGT2B7 genotypes on plasma concentration of valproic acid: a meta-analysis

@article{Wang2017EffectOU,
  title={Effect of UGT2B7 genotypes on plasma concentration of valproic acid: a meta-analysis},
  author={Ping Wang and Xiao-qian Lin and Wen-Ke Cai and Gui-li Xu and Meng-Di Zhou and Mei Yang and Gong-Hao He},
  journal={European Journal of Clinical Pharmacology},
  year={2017},
  volume={74},
  pages={433-442}
}
Valproic acid (VPA) is one of the most widely used antiepileptic drugs. Recently, increasing evidence suggested that polymorphisms in UGT2B7 gene were associated with VPA pharmacokinetics, but results remained controversial. Therefore, a meta-analysis was performed to derive a more precise evaluation between C802T, C161T, and G211T polymorphisms and plasma… CONTINUE READING