Effect of Tetraalkylammonium Derivative of 6-Methyluracil on Amplitude and Temporal Parameters of Miniature Endplate Potentials in Frog Neuromuscular Junction

@article{Gorshkova2001EffectOT,
  title={Effect of Tetraalkylammonium Derivative of 6-Methyluracil on Amplitude and Temporal Parameters of Miniature Endplate Potentials in Frog Neuromuscular Junction},
  author={O. V. Gorshkova and Vladimir V. Zobov and Ella A Bukharaeva and E. E. Nikol'skii and V. D. Akamsin and I. V. Galyametdinova and Vladimir S. Reznik},
  journal={Bulletin of Experimental Biology and Medicine},
  year={2001},
  volume={131},
  pages={446-450}
}
The effect of C-547, a tetraalkylammonium derivative of 6-methyluracil, a novel highly selective acetylcholinesterase inhibitor, on frog neuromuscular junction was studied. In concentrations 10-9-10-7 M the preparation increased the amplitude and temporal parameters of miniature endplate potentials. In contrast to the effect of C-574 on purified… CONTINUE READING