Effect of Terminal-Group Functionality on the Ability of Dendrimers to Bind Proteins.

@article{Chiba2017EffectOT,
  title={Effect of Terminal-Group Functionality on the Ability of Dendrimers to Bind Proteins.},
  author={Fumiko Chiba and Lance J Twyman},
  journal={Bioconjugate chemistry},
  year={2017},
  volume={28 8},
  pages={2046-2050}
}
It is known that dendrimers can bind proteins with good selectively. This selectivity comes about from an optimization based on matching the size of the dendrimer with the size of the protein's interfacial binding area. In this paper, we report how this selectivity can be moderated by the functionality on the surface of the dendrimer. Specifically, we… CONTINUE READING