Effect of TGF- 2 and Anti–TGF- 2 Antibody in a New In Vivo Rodent Model of Posterior Capsule Opacification


METHODS. An extracapsular lens extraction (ECLE) was performed in 72 Sprague–Dawley rats. At the end of the procedure, 10 L TGF2 (TGF2–treated group), fetal calf serum (FCS)/phosphate-buffered saline (PBS; FCS/PBS-treated control group), a human monoclonal TGF2 antibody (anti–TGF2– treated group), or a null control IgG4 antibody (null antibody– treated… (More)


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