Effect of T helper cell 1/T helper cell 2 balance and nuclear factor-κB on white matter injury in premature neonates.

  title={Effect of T helper cell 1/T helper cell 2 balance and nuclear factor-$\kappa$B on white matter injury in premature neonates.},
  author={Xuewen Su and Haifeng Yuan and Hongwei Cui and Hua Zhu and Xia Yun and Wenyan Tang and Junlong Chen and Zu Luan},
  journal={Molecular medicine reports},
  volume={17 4},
Incidence of white matter injury (WMI), which is featured as softening of white matter tissues, has recently increased. Previous studies have demonstrated a close correlation between T helper cell 1 and T helper cell 2 (Th1/Th2) imbalance and nuclear factor‑κB (NF‑κB) with brain disease. Their role in premature WMI, however, remains to be illustrated. Serum samples were collected from 60 premature WMI neonates, plus another control group of 60 premature babies without WMI. Patients were further… Expand
5 Citations
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  • Xuejiao Huang, JianHua Fu
  • Medicine
  • Frontiers in Pediatrics
  • 2021
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Th1, Th2, Th17 and Treg levels in umbilical cord blood in preeclampsia
  • M. I. Vargas-Rojas, H. Solleiro-Villavicencio, E. Soto-Vega
  • Medicine
  • The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  • 2016
The results show that there is a shift, in the Th1/Th2, and the Th17/Treg balance, favoring skewness towards a proinflammatory status in the umbilical cord blood in preeclampsia. Expand
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Preterm white matter brain injury is prevented by early administration of umbilical cord blood cells
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