Effect of Synaptic Transmission on Viral Fitness in HIV Infection

Abstract

HIV can spread through its target cell population either via cell-free transmission, or by cell-to-cell transmission, presumably through virological synapses. Synaptic transmission entails the transfer of tens to hundreds of viruses per synapse, a fraction of which successfully integrate into the target cell genome. It is currently not understood how… (More)
DOI: 10.1371/journal.pone.0048361

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@inproceedings{Komarova2012EffectOS, title={Effect of Synaptic Transmission on Viral Fitness in HIV Infection}, author={Natalia L. Komarova and David N. L. Levy and Dominik Wodarz}, booktitle={PloS one}, year={2012} }