Effect of Sustained Inflations vs Intermittent Positive Pressure Ventilation on Bronchopulmonary Dysplasia or Death Among Extremely Preterm Infants: The SAIL Randomized Clinical Trial

@article{Kirpalani2019EffectOS,
  title={Effect of Sustained Inflations vs Intermittent Positive Pressure Ventilation on Bronchopulmonary Dysplasia or Death Among Extremely Preterm Infants: The SAIL Randomized Clinical Trial},
  author={H. Kirpalani and S. Ratcliffe and M. Keszler and P. Davis and E. Foglia and A. T. te Pas and Melissa Fernando and Aasma S. Chaudhary and R. Localio and A. V. van Kaam and W. Onland and L. Owen and G. Schm{\"o}lzer and A. Katheria and H. Hummler and G. Lista and S. Abbasi and D. Klotz and B. Simma and V. Nadkarni and F. Poulain and S. Donn and H. Kim and W. Park and Claudia T. Cadet and Juin Yee Kong and A. Smith and {\'U}. Guill{\'e}n and H. Liley and A. Hopper and M. Tamura},
  journal={JAMA},
  year={2019},
  volume={321},
  pages={1165–1175}
}
Importance Preterm infants must establish regular respirations at delivery. Sustained inflations may establish lung volume faster than short inflations. Objective To determine whether a ventilation strategy including sustained inflations, compared with standard intermittent positive pressure ventilation, reduces bronchopulmonary dysplasia (BPD) or death at 36 weeks’ postmenstrual age without harm in extremely preterm infants. Design, Setting, and Participants Unmasked, randomized clinical trial… Expand
Sustained inflation breaths at birth were not beneficial for extremely preterm infants
Gradual Aeration at Birth is More Lung Protective than a Sustained Inflation in Preterm Lambs.
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References

SHOWING 1-10 OF 41 REFERENCES
Sustained Lung Inflation at Birth for Preterm Infants: A Randomized Clinical Trial
Sustained versus intermittent lung inflation for resuscitation of preterm infants: a randomized controlled trial
Sustained inflation versus positive pressure ventilation at birth: a systematic review and meta-analysis
Sustained versus standard inflations during neonatal resuscitation to prevent mortality and improve respiratory outcomes.
Effects of a sustained inflation in preterm infants at birth.
...
1
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4
5
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