• Corpus ID: 101487060

Effect of Superfine Comminution on Pharmacokinetics of Ferulic Acid in Rhizoma Chuanxiong in Rabbits

@article{Qiang2010EffectOS,
  title={Effect of Superfine Comminution on Pharmacokinetics of Ferulic Acid in Rhizoma Chuanxiong in Rabbits},
  author={Liu Qiang},
  journal={The Chinese Pharmaceutical Journal},
  year={2010}
}
  • L. Qiang
  • Published 2010
  • Chemistry
  • The Chinese Pharmaceutical Journal
OBJECTIVE To study the effect of superfine comminution on pharmacokinetics of ferulic acid(FA) in Rhizoma Chuanxiong in rabbits.METHODS The rabbits were given orally Rhizoma 10 g·kg-1 and blood samples were drawn from the rabbits' ear arteries.FA in the serum of rabbits was determined by HPLC.The separation was performed on a Thermo Hypersil GOLD-C18 column(4.6 mm×250 mm,5 μm) at the temperature of 30 ℃.The mobile phase consisted of methanol-water(containing 0.5% acetic acid)(20∶80) at the flow…