Effect of Short-Term Oral Valproic Acid on Vision and Visual Field in Retinitis Pigmentosa

  title={Effect of Short-Term Oral Valproic Acid on Vision and Visual Field in Retinitis Pigmentosa},
  author={P. Mahesh Shanmugam and C. K. Minija and Rajesh Ramanjulu and Pradeep Tekwani and Manish Saxena},
  booktitle={Ophthalmology and therapy},
INTRODUCTION The aim of this study was to evaluate the effect of short-term oral valproic acid (VPA) on the vision and visual fields of patients with retinitis pigmentosa (RP). METHODS In this prospective, nonrandomized trial, 10 patients (20 eyes) with established RP were treated with oral VPA 500 mg/day for 3 months. Visual acuity was monitored using the Snellen chart and values were converted into Early Treatment Diabetic Retinopathy Study chart and logarithm of the minimum angle of… CONTINUE READING


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Showing 1-10 of 12 references

First order dynamics of visual field loss in retinitis pigmentosa

R Massof, G Dagnelie, T Benzschawel
Clin Vision Sci. 1990;5:1–26 • 2012
View 1 Excerpt

The conclusions of Clemson et al. concerning valproic acid are premature

MJ Van Schooneveld, LI van den Born, M van Genderen
Br J Ophthalmol • 2011
View 1 Excerpt

A pilot study of topical treatment with an alpha2-agonist in patients with retinal dystrophies.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics • 2008
View 2 Excerpts

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