Effect of Secreted Molecules of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells on Acute Hepatic Failure Model.

@article{Lotfinia2016EffectOS,
  title={Effect of Secreted Molecules of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells on Acute Hepatic Failure Model.},
  author={Majid Lotfinia and Mehdi Kadivar and Abbas Piryaei and Behshad Pournasr and Soroush Sardari and Niloofar Sodeifi and Forugh-Azam Sayahpour and Hossein Baharvand},
  journal={Stem cells and development},
  year={2016},
  volume={25 24},
  pages={1898-1908}
}
Adult tissue-derived mesenchymal stem cells (MSCs) show tremendous promise for a wide array of therapeutic applications predominantly through paracrine activity. Recent reports showed that human embryonic stem cell (ESC)-derived MSCs are an alternative for regenerative cellular therapy due to manufacturing large quantities of MSCs from a single donor. However, no study has been reported to uncover the secretome of human ESC-MSCs as treatment of an acute liver failure (ALF) mouse model. We… CONTINUE READING
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