Effect of Sandostatin LAR on sleep apnoea in acromegaly: correlation with computerized tomographic cephalometry and hormonal activity.

@article{Ip2001EffectOS,
  title={Effect of Sandostatin LAR on sleep apnoea in acromegaly: correlation with computerized tomographic cephalometry and hormonal activity.},
  author={Mary S M Ip and Kathryn C. B. Tan and Wilfred C. G. Peh and Karen S. L. Lam},
  journal={Clinical endocrinology},
  year={2001},
  volume={55 4},
  pages={477-83}
}
OBJECTIVES Sleep apnoea has been reported to occur in subjects with acromegaly. This study evaluates the relationship among biochemical activity, sleep apnoeic activity and upper airway anatomic profile in acromegaly, and the effect of Sandostatin LAR, a long-acting somatostatin analogue, on these parameters. PATIENTS Fourteen subjects with acromegaly were recruited. MEASUREMENTS Subjects were assessed at baseline and those with apnoea-hypopnoea index (AHI) > or = 5 were reassessed after 6… CONTINUE READING

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