Effect of SCP-x gene ablation on branched-chain fatty acid metabolism.

@article{Atshaves2007EffectOS,
  title={Effect of SCP-x gene ablation on branched-chain fatty acid metabolism.},
  author={Barbara P. Atshaves and Avery L McIntosh and Danilo Landrock and Harold Ross Payne and John T. Mackie and Nobuyo Maeda and Judith Ball and Friedhelm Schroeder and Ann B. Kier},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2007},
  volume={292 3},
  pages={
          G939-51
        }
}
Despite the importance of peroxisomal oxidation in branched-chain lipid (phytol, cholesterol) detoxification, little is known regarding the factors regulating the peroxisomal uptake, targeting, and metabolism of these lipids. Although in vitro data suggest that sterol carrier protein (SCP)-x plays an important role in branched-chain lipid oxidation, the full physiological significance of this peroxisomal enzyme is not completely clear. To begin to resolve this issue, SCP-x-null mice were… CONTINUE READING

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