Effect of Resveratrol on Oxidative Stress and Mitochondrial Dysfunction in Immature Brain during Epileptogenesis

@article{Folbergrov2018EffectOR,
  title={Effect of Resveratrol on Oxidative Stress and Mitochondrial Dysfunction in Immature Brain during Epileptogenesis},
  author={Jaroslava Folbergrov{\'a} and Pavel Je{\vs}ina and Hana Kubov{\'a} and Jakub Ot{\'a}hal},
  journal={Molecular Neurobiology},
  year={2018},
  volume={55},
  pages={7512-7522}
}
The presence of oxidative stress in immature brain has been demonstrated during the acute phase of status epilepticus (SE). The knowledge regarding the long periods of survival after SE is not unequivocal, lacking direct evidence. To examine the presence and time profile of oxidative stress, its functional effect on mitochondria and the influence of an antioxidant treatment in immature rats during epileptogenesis, status epilepticus (SE) was induced in immature 12-day-old rats by Li-pilocarpine… CONTINUE READING

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