Effect of Rebamipide on the Premalignant Progression of Chronic Gastritis: A Randomized Controlled Study.

@article{Han2015EffectOR,
  title={Effect of Rebamipide on the Premalignant Progression of Chronic Gastritis: A Randomized Controlled Study.},
  author={Xue Han and Kui Jiang and Bangmao Wang and Lu Zhou and Xin Chen and Shu Li},
  journal={Clinical drug investigation},
  year={2015},
  volume={35 10},
  pages={665-73}
}
BACKGROUND AND OBJECTIVE Chronic gastritis frequently progresses into precancerous intestinal metaplasia and intraepithelial neoplasia lesions. Rebamipide is a free radical scavenger and we assessed its efficacy on clinical symptoms, gastric mucosal lesions, pathologic grade, and immunohistochemistry in chronic gastritis patients. METHODS 178 eligible patients were randomized into treatment and control groups. Both groups followed an optimized lifestyle for 26 weeks, but the treatment group… CONTINUE READING