Effect of Quinolones on the Human Intestinal Microflora

@article{Nord1995EffectOQ,
  title={Effect of Quinolones on the Human Intestinal Microflora},
  author={Dr Carl Erik Nord},
  journal={Drugs},
  year={1995},
  volume={49},
  pages={81-85}
}
The quinolones exhibit a selective suppressive effect on the intestinal microflora. The aerobic Gram-negative bacteria are strongly suppressed, while the aerobic Gram-positive bacteria are less affected, with ciprofloxacin and ofloxacin having the greatest effect. The anaerobic microflora is not affected by administration of norfloxacin, but is suppressed slightly by ciprofloxacin and ofloxacin, and moderately by sparfloxacin and temafloxacin. Very high concentrations of the quinolones are… CONTINUE READING

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European Journal of Clinical Microbiology and Infectious Diseases • 1990

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