Effect of Punica granatum (pomegranate) juice extract on healthy liver and hepatotoxicity induced by diethylnitrosamine and phenobarbital in male rats.

@article{Shaban2014EffectOP,
  title={Effect of Punica granatum (pomegranate) juice extract on healthy liver and hepatotoxicity induced by diethylnitrosamine and phenobarbital in male rats.},
  author={Nadia Z. Shaban and Mohamed A R El-Kersh and Mohamed M Bader-Eldin and Sosan Amin Kato and Asmaa F Hamoda},
  journal={Journal of medicinal food},
  year={2014},
  volume={17 3},
  pages={339-49}
}
The effect of pomegranate juice (PJ) on hepatic antioxidant enzyme activities, lipid peroxidation, DNA fragmentation (DNAF), and caspase-3 activity in rats both treated and not treated with diethylnitrosamine (DEN) and phenobarbital (PB) was studied. Administration of rats with DEN and PB caused an elevation in the levels of malondialde-hyde (MDA), DNAF, and activities of glutathione reductase (GSR) and caspase-3, while the activities of superoxide dismutase, glutathione S-transferase, total… CONTINUE READING
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