Corpus ID: 26330744

Effect of Pumpkin Seed (Cucurbita pepo L.) Diets on Benign Prostatic Hyperplasia (BPH): Chemical and Morphometric Evaluation in Rats

@inproceedings{Abdelrahman2006EffectOP,
  title={Effect of Pumpkin Seed (Cucurbita pepo L.) Diets on Benign Prostatic Hyperplasia (BPH): Chemical and Morphometric Evaluation in Rats},
  author={M. Abdel-rahman},
  year={2006}
}
Benign prostatic hyperplasia (BPH) is a common disease in elderly men. Although it is a non- malignant disease, it can have a significant impact on the quality of life of elderly men. The pumpkin seed is claimed to be useful in the management of BPH. This investigation analysed the chemical composition of pumpkin seeds and examined its effect on citral-induced hyperplasia of the prostate in Wistar rats. Citral was administered orally into stomachs of male rats to induce BPH to all rats except… Expand

Figures and Tables from this paper

Cucurbita pepo inhibits benign prostatic hyperplasia induced by testosterone in sprague-dawley rats. (c2011)
The Cucurbita pepo (pumpkin) seeds are used to treat benign prostatic hyperplasia (BPH). This study examines the effects of pumpkin seeds on dihydrotestosterone produced from testosterone thatExpand
Inhibitory effects of Nigella sativa seed oil on the testosterone-induced benign prostatic hyperplasia in rats
Background: Benign prostatic hyperplasia (BPH) is the most prevalent disease of the prostate in elderly men. Since Nigella sativa has been reported to show various pharmacological effects, this studyExpand
Inhibitory effect of Coffea arabica bean in testosterone induced prostatic hyperplasia in Sprague-Dawley rats
Benign prostatic hyperplasia (BPH) has been described as the uncontrolled prostate gland growth which leads to difficulty in urination. One of the treatment of BPH is saw palmetto lipid extractsExpand
PHYTOTHERAPEUTIC APPROACH TO BENIGN PROSTATIC HYPERPLASIA TREATMENT BY PUMPKIN SEED (CUCURBITA PEPO L., CUCURBITACEAE)
TLDR
Herbal medicines are promising in mild to moderate BPH, which is a noncancerous enlargement of the prostate gland caused by proliferation of both stromal and epithelial cells. Expand
Effect of hydroalcoholic extract of pumpkin seeds on start of oogenesis and change of hormone-pituitary-ovarian axis in immature rats
Introduction: Pumpkin seed has been used in traditional medicine as a drug for improving sexual function and vigor. We did not find sufficient scientific evidence to support it. The present study wasExpand
Protective Effect of Allium cepa ( Onion ) Seeds ( AC ) Extract on Histopathology of Testis in STZ-Induced Male Rats
The aim of the present study was to evaluate the effect of the extract of Allium cepa (Onion) seeds (AC) on morphometric and histology of testis and biochemical parameters in STZ-induced male rats.Expand
The effect of Hydro-alcoholic extract of pumpkin seeds on Oogenesis and Hormone-Pituitary-Ovarian Axis in Mature Rats
TLDR
Injecting hydro-alcoholic extract of pumpkin seeds increases significantly the oogenesis procedure, LH, FSH, estrogen and progesterone levels and decreases significantly the left ovaries' weight and number of primordial, primary, and secondary follicles in experimental groups in contrast to control group (P<0.05). Expand
Effects of aqueous Cucurbita pepo Linn seed extract on some haematological parameters and serum electrolytes of lactating albino rats
Thepresent study investigated the effects of aqueous Cucurbita pepo Linn seedextract on some haematological parameters and serum electrolyte concentrationof lactating albino rats. A total of twentyExpand
Protective effect of Pumpkin seed extract on sperm characteristics, biochemical parameters and epididymal histology in adult male rats treated with Cyclophosphamide
TLDR
The findings indicated that pumpkin seed extract might be used as protective agent against CP‐induced reproductive toxicity and could improve the above‐mentioned parameters remarkably in CP‐treated rats. Expand
Effects of an Oil-Free Hydroethanolic Pumpkin Seed Extract on Symptom Frequency and Severity in Men with Benign Prostatic Hyperplasia: A Pilot Study in Humans
TLDR
The results indicate that the oil-free hydroethanolic pumpkin seed extract seems to be a very well tolerable, appropriate plant extract to support health benefits in a collective suffering from BPH related symptoms without the need of medical treatment. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 15 REFERENCES
Citral and testosterone interactions in inducing benign and atypical prostatic hyperplasia in rats.
TLDR
The results demonstrate an induction of benign as well as atypical prostatic hyperplasia following citral application and suggest a synergism between citral and testosterone resulting in hyperplastic changes in the rat ventral prostate. Expand
Role of chronic inflammation in the promotion of prostatic hyperplasia in rats.
TLDR
Investigation of the effect of the immunomodulator compounds, Complete Freund Adjuvant (CFA) and cyclosporin A (CsA), administered alone or together with citral on the induction and extent of rat prostatic hyperplasia found them to play a role in the prostatic epithelial cell growth and proliferation processes. Expand
Treatment of benign prostatic hyperplasia with phytosterols.
TLDR
Urinary flow, micturition time, residual urine, frequency of mictsurition and a subjective assessment of the effect of treatment were all significantly improved in the treatment group. Expand
African Cucurbita pepo L.: properties of seed and variability in fatty acid composition of seed oil.
TLDR
Pumpkin (Cucurbita pepo) seeds are used locally in Eritrea to treat tapeworm and contains an appreciable amount of unsaturated fatty acids and is found to be a rich source of linoleic acid. Expand
Changes in chemical composition of pumpkin seeds during the roasting process for production of pumpkin seed oil (Part 1: non-volatile compounds)
Abstract Pumpkin seed oil is a common salad oil in Austria. It is not only of interest because of its typical taste but also because of its potential in curing prostate disease. Besides the fattyExpand
[Prosta Fink Forte capsules in the treatment of benign prostatic hyperplasia. Multicentric surveillance study in 2245 patients].
TLDR
Prosta Fink Forte facilitates an efficient improvement of BPH symptoms, especially in early stages, in patients suffering from benign prostate hyperplasia. Expand
Use of 5α-reductase inhibitors to prevent benign prostatic hyperplasia disease
TLDR
This work can identify men with an enlarged prostate at risk for BPH disease who may be candidates for preventive therapy with 5ARIs, regardless of urinary symptoms or bother. Expand
Chemical characteristics of oils from naked and husk seeds of Cucurbita pepo L.
Pumpkin seed oils from naked and husk pumpkin seeds, produced by an industrial process and by laboratory extraction, were evaluated for fatty acid composition, tocopherol, sterol and squaleneExpand
AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet.
TLDR
Two new diets may prove to be a better choice than AIN-76A for long-term as well as short-term studies with laboratory rodents because of a better balance of essential nutrients. Expand
Prosta Fink Forte®-Kapseln in der Behandlung der benignen Prostatahyperplasie. Eine multizentrische Anwendungsbeobachtung an 2245 Patienten
TLDR
Prosta Fink Forte facilitates an efficient improvement of BPH symptoms, especially in early stages, in a multicentric clinical trial in 2,245 patients. Expand
...
1
2
...