Effect of Pulsed Estrogen Therapy on Hemostatic Markers in Comparison with Oral Estrogen Regimen in Postmenopausal Women

@article{Basurto2006EffectOP,
  title={Effect of Pulsed Estrogen Therapy on Hemostatic Markers in Comparison with Oral Estrogen Regimen in Postmenopausal Women},
  author={L. Basurto and R. Saucedo and A. Zarate and C. Mart{\'i}nez and E. Gaminio and E. Reyes and Marcelino Hern{\'a}ndez},
  journal={Gynecologic and Obstetric Investigation},
  year={2006},
  volume={61},
  pages={61 - 64}
}
Background/Aims: Hormone replacement therapy (HRT) is associated with an increased risk of thromboembolism dependent on the type of HRT; therefore, we compared therapy effects of intranasal with oral estrogens on coagulation and fibrinolysis markers in postmenopausal women. Methods: A randomized study in which 29 healthy hysterectomized women received intranasal 17β-estradiol or oral estrogens for 3 months. Results: There were no significant differences in the baseline characteristics between… Expand
Hormone therapy and hemostasis among postmenopausal women: a review
Circulating levels of plasminogen activator inhibitor-1 are associated with metabolic syndrome rather than with menopause
Menopausal women have hypofibrinolysis even in subclinical stage of atherosclerosis.
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