Effect of Pulsed Estrogen Therapy on Hemostatic Markers in Comparison with Oral Estrogen Regimen in Postmenopausal Women

  title={Effect of Pulsed Estrogen Therapy on Hemostatic Markers in Comparison with Oral Estrogen Regimen in Postmenopausal Women},
  author={Lourdes Feria Basurto and Renata Saucedo and Arturo Zarate and Carlos Mart{\'i}nez and Elizabeth Gaminio and Elba Reyes and Marcelino Hern{\'a}ndez},
  journal={Gynecologic and Obstetric Investigation},
  pages={61 - 64}
Background/Aims: Hormone replacement therapy (HRT) is associated with an increased risk of thromboembolism dependent on the type of HRT; therefore, we compared therapy effects of intranasal with oral estrogens on coagulation and fibrinolysis markers in postmenopausal women. Methods: A randomized study in which 29 healthy hysterectomized women received intranasal 17β-estradiol or oral estrogens for 3 months. Results: There were no significant differences in the baseline characteristics between… 

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