Effect of Psoralea corylifolia extract on physically induced depression in mice.

  title={Effect of Psoralea corylifolia extract on physically induced depression in mice.},
  author={D. Bhawya and Kandangath Raghavan Anilakumar and Farhath Khanum},
  journal={life science journal},
The mouse forced swimming test (FST) and tail suspension test (TST) are widely used to predict anti-depressant efficacy indicated by immobility time to be reduced by several different classes of anti-depressant drugs. PCE feeding at the dose of 75,150 and 300 mg/kg reduced the immobility duration at 14-days and 21-days, however the decrease was significant in mice treated with PCE for 21-days also, extract had no effect on spontaneous motor activity in mice, indicating that extract had no… Expand

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