Effect of Proton Pump Inhibitors on Vitamins and Iron

@article{McColl2009EffectOP,
  title={Effect of Proton Pump Inhibitors on Vitamins and Iron},
  author={K. McColl},
  journal={The American Journal of Gastroenterology},
  year={2009},
  volume={104},
  pages={S5-S9}
}
  • K. McColl
  • Published 2009
  • Medicine
  • The American Journal of Gastroenterology
Vitamin C is actively secreted in human gastric juice. Proton pump inhibitor therapy lowers the concentration of vitamin C in gastric juice and the proportion of the vitamin in its active antioxidant form i.e., ascorbic acid. This has secondary effects on intragastric nitrite chemistry, resulting in a rise in gastric juice nitrite levels. There is also some evidence that proton pump inhibitors may reduce the bioavailability of ingested vitamin C. The effect of proton pump inhibitors on vitamin… Expand
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