Effect of Porphyromonas gingivalis lipopolysaccharide, tumor necrosis factor-alpha, and interleukin-1beta on calprotectin release in human monocytes.

@article{Suryono2003EffectOP,
  title={Effect of Porphyromonas gingivalis lipopolysaccharide, tumor necrosis factor-alpha, and interleukin-1beta on calprotectin release in human monocytes.},
  author={Suryono and Jun-ichi Kido and Noriko Hayashi and Masatoshi Kataoka and Toshihiko Nagata},
  journal={Journal of periodontology},
  year={2003},
  volume={74 12},
  pages={1719-24}
}
BACKGROUND Calprotectin is a major cytosolic protein of monocytes, granulocytes, and epithelial cells. It is known that calprotectin is released in inflammatory tissues and detected in gingival crevicular fluid (GCF) of periodontitis patients at high levels. The origin of calprotectin in GCF and its regulation in periodontal disease are unknown. In this study, we investigated the distribution of calprotectin in gingival tissue with inflammation and the induction of calprotectin release from… CONTINUE READING