Effect of Peritoneal Lavage with Taurolidine on Primary Colonic Anastomosis in a Rat Model of Secondary Peritonitis

@article{Akku2005EffectOP,
  title={Effect of Peritoneal Lavage with Taurolidine on Primary Colonic Anastomosis in a Rat Model of Secondary Peritonitis},
  author={Aşkın Akkuş and M. G{\"u}lmen and Ayhan Cevik and N. Bildik and Orhan Şad and E. {\"O}zt{\"u}rk and N. Barışık},
  journal={Surgery Today},
  year={2005},
  volume={36},
  pages={436-440}
}
PurposeThe reported antibacterial, antiendotoxic, and antiadhesive effects of taurolidine prompted us to study the benefits of intraperitoneal lavage with taurolidine on primary colonic anastomosis in a rat model of secondary peritonitis.MethodsWe induced peritonitis in 40 rats by injecting Escherichia coli isolate intraperitoneally. We performed colonic resection and primary anastomosis 5 h later, after lavage with either taurolidine or saline solution. After the rats were killed, on… Expand
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