Effect of PPARG on AGEs-induced AKT/MTOR signaling-associated human chondrocytes autophagy.

Abstract

Accumulation of advanced glycation end products (AGEs) in articular cartilage is thought to represent a major risk factor for osteoarthritis development. In this study we aimed to probe the role of AGEs in human chondrocytes and to determine the impact of the peroxisome proliferator-activated receptor-γ (PPARG) on AGEs-induced cell autophagy. Cell viability… (More)
DOI: 10.1002/cbin.10951

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